Immobilized poly(n)polymerase

US11384375B2 · kind B2 · utility

Assignee

• CureVac AG · DE

Inventors

• Tilmann ROOS · Aspenhausiedlung, DE
• Benyamin YAZDAN PANAH · Tübingen, DE
• Markus CONZELMANN · Tübingen, DE
• Veronika Wagner · Tübingen, DE

Key dates

• Filing date: May 2, 2016
• Grant date: Jul 12, 2022
• Expiry date: May 2, 2036

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/50
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to an immobilized poly(N)polymerase (PNP), methods of producing said PNP and uses thereof. Further disclosed is an enzyme reactor and kit comprising the PNP for producing polynucleotidylated ribonucleic acid poly(N)RNA)molecules which are useful in gene therapy, immunotherapy, protein replacement therapy and/or vaccination.