Patent · US Active

Time of flight mass spectrometer and method of mass spectrometry

US11387094B2 · kind B2 · utility

0Cited by

5References

25Claims

0Family size

Assignee

THERMO FISHER SCIENTIFIC (BREMEN) GMBH · DE

Inventors

Hamish Stewart · Bremen, DE
Dmitry Grinfeld · Bremen, DE
Alexander A. Makarov · Bremen, DE

Key dates

Filing date	Mar 2, 2021
Grant date	Jul 12, 2022
Priority date	—
Expiry date	Mar 2, 2041

Classification

Technology area (CPC H)Electricity
CPC primaryH01J49/446
WIPO fieldElectrical machinery, apparatus, energy
WIPO sectorElectrical engineering

Abstract

A time-of-flight (ToF) mass spectrometer, comprising: a pulsed ion injector for forming an ion beam that travels along an ion path; a detector for detecting ions in the ion beam that arrive at the detector at times according to their m/z values; an ion focusing arrangement located between the ion injector and the detector for focusing the ion beam in at least one direction orthogonal to the ion path; and a variable voltage supply for supplying the ion focusing arrangement with at least one variable voltage that is dependent on a charge state and/or an amount of ions of at least one species of ions in the ion beam. A corresponding method of mass spectrometry is provided. The charge state and/or an amount of ions may be acquired from a pre-scan, or predicted. Tuning of the spectrometer based on a charge state and/or an amount of ions of at least one species of ions in the ion beam may be performed on the fly.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.