Therapeutic combinations of orally administered docetaxel and a P-gp inhibitor for the treatment of cancer
US11389442B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Oct 29, 2020 |
| Grant date | Jul 19, 2022 |
| Priority date | — |
| Expiry date | Oct 29, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides pharmaceutical combinations of orally administered docetaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity-type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered docetaxel (e.g., Taxotere® or docetaxel formulated with polysorbate 80) therapy in a subject suffering from cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.