Arginase inhibitors as therapeutics
US11389464B2 · kind B2 · utility
1Cited by
25References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 19, 2020 |
| Grant date | Jul 19, 2022 |
| Priority date | — |
| Expiry date | Jun 21, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/025
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds according to Formula I are potent inhibitors of Arginase I and II activity: where R1, R2, R3, R4, D, W, X, Y, and Z are defined in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use in treating or preventing a disease or a condition associated with arginase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.