Patent · US Active

Methods and processes for the preparation of KDM1A inhibitors

US11390590B2 · kind B2 · utility

3Cited by

5References

28Claims

0Family size

Assignee

Imago Biosciences, Inc. · US

Inventors

Amy E. Tapper · Boston, US
Cassandra Celatka · Hull, US
Arthur Glenn Romero · Kalamazoo, US
John M. McCall · Kalamazoo, US
Toni Chancellor · Palomar Park, US
Jian-Xie Chen · Fryeburg, US
Xuemei Chen · Yichang City, CN
He Zhao · Madison, US
Betina Biolatto · Delmar, US
Elisabeth C. A. Brot · Albany, US
Zhihua Li · Changsha, CN
Xiaoming Liao · Beijing, CN

Key dates

Filing date	Aug 16, 2017
Grant date	Jul 19, 2022
Priority date	—
Expiry date	Nov 11, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive animation of cyclopropylamines.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.