Patent · US Active

Vascular endothelial growth factor/anti-fibronectin antibody fusion proteins

US11390666B2 · kind B2 · utility

0Cited by
14References
4Claims
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Assignee

Inventors

Key dates

Filing dateJun 6, 2018
Grant dateJul 19, 2022
Priority date
Expiry dateJun 6, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/33
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The application relates to a fusion protein comprising an antibody molecule, or antigen-binding fragment thereof, and a member of the vascular endothelial growth factor family, such as VEGF-C or VEGF-D. The antibody molecule preferably binds an antigen associated with angiogenesis, such as the ED-A isoform of fibronectin. In particular, the application relates to the therapeutic use of such fusion protein in the treatment of an inflammatory disease or disorder.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.