Multispecific heavy chain antibodies with modified heavy chain constant regions
US11390681B2 · kind B2 · utility
5Cited by
21References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 14, 2021 |
| Grant date | Jul 19, 2022 |
| Priority date | — |
| Expiry date | Jun 14, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Multispecific, human heavy chain antibodies (e.g., UniAbs™) that have modified heavy chain constant regions that impart advantageous properties are provided. The invention further concerns methods of making such antibodies, compositions, including pharmaceutical compositions, comprising such antibodies, and their use to treat disorders that are characterized by expression of one or more of the binding targets described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.