Systems and methods for high throughput compound library creation
US11393560B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 14, 2018 |
| Grant date | Jul 19, 2022 |
| Priority date | — |
| Expiry date | Apr 20, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16C20/64
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The disclosure provides methods and systems for identifying a subset of compounds in a plurality of compounds. The identifying includes obtaining, for each compound, a vector including a set of elements, where each element includes a measurement of a different feature of an instance of a cell context upon exposure to the compound. The identifying includes repeating the obtaining for a plurality of cell contexts, to obtain a plurality of vectors for each compound across different cell contexts. The identifying includes combining the vectors for each compound to form a combined vector for each compound, thereby forming a plurality of combined vectors representing different compounds. The identifying includes pruning the plurality of compounds to the subset of compounds based on a similarity between respective combined vectors in the plurality of combined vectors corresponding to compounds in the plurality of compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.