Tumour immunogen, preparation method therefor, and application
US11396642B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 11, 2017 |
| Grant date | Jul 26, 2022 |
| Priority date | — |
| Expiry date | Jan 30, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M41/48
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are a tumour immunogen, a preparation method therefore, and an application. After localised sequential cooling-heating treatment is performed on tumour tissue and/or cells, the tumour tissue and/or cells release a large amount of tumour immunogen heat shock protein 70. The obtained tumour immunogen can activate the body's tumour immune system, to convert immunosuppressive cells into mature dendritic cells, thereby increasing immunogen presentation, and activating tumour immunity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.