Patent · US Active

Stable protease variants

US11396648B2 · kind B2 · utility

0Cited by

0References

13Claims

0Family size

Assignee

EW NUTRITION GMBH · DE

Inventors

Andreas Michels · Mülheim an der Ruhr, DE
Andreas Scheidig · Cologne, DE
Christian Elend · Friedland, DE
Claudia Krapp · Cologne, DE
Thomas Horn · Boston, US

Key dates

Filing date	Dec 22, 2017
Grant date	Jul 26, 2022
Priority date	—
Expiry date	Dec 22, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y304/21
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a protease variant which is at least 90% identical to the full length amino acid sequence of a Kumamolisin AS backbone as set forth in any of SEQ ID NOs 1-3, while maintaining proteolytic activity, or a fragment, fraction or shuffled variant thereof maintaining proteolytic activity, which protease variant demonstrates altered or improved stability compared to the Kumamolisin AS wildtype as set forth in SEQ ID NO 4, or the Kumamolisin AS backbone as set forth in any of SEQ ID NOs 1-3.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.