Patent · US Active

System for the biocontrol of disease-transmitting mosquitoes and their eggs using horizontally transferable symbiotic bacteria to deliver pathogen specific interfering RNA polynucleotides

US11396653B2 · kind B2 · utility

0Cited by

0References

14Claims

0Family size

Assignees

Pebble Labs Inc. · US
COLORADO STATE UNIVERSITY RESEARCH FOUNDATION · US

Inventors

Richard T. Sayre · Worthington, US
Jiannong Xu · Westlake, US
Bradley R. Borlee · Madison, US
Konstantinos Lymperopoulos · Los Alamos, US
Rebekah Kading · Fort Collins, US
William A. Black · Durham, US
Kenneth C. Olson · Burlingame, US
Carol Blair · Fort Collins, US

Key dates

Filing date	Jul 10, 2018
Grant date	Jul 26, 2022
Priority date	—
Expiry date	Oct 11, 2039

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldBasic materials chemistry
WIPO sectorChemistry

Abstract

The inventive technology relates to novel paratransgenic strategies for the control of pathogens. The inventive technology may specifically include a novel paratransgenic system configured to deliver one or more inhibitory RNA molecules to pathogen/disease-transmitting organisms. In a preferred embodiment, the invention may include one or more genetically engineered symbiotic bacteria configured to persist throughout the life-cycle of a mosquito and deliver one or more interfering RNA molecules to pathogen/disease-transmitting mosquitoes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.