Method for preparing pharmaceutical composition for preventing or treating cognitive impairment-related disease and pharmaceutical composition for preventing or treating cognitive impairment-related disease prepared by the same
US11400085B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 19, 2019 |
| Grant date | Aug 2, 2022 |
| Priority date | — |
| Expiry date | Mar 19, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1682
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for preparing a pharmaceutical composition for preventing or treating a cognitive impairment-related disease and a pharmaceutical composition for preventing or treating a cognitive impairment-related disease prepared by the same, and the pharmaceutical composition includes microparticles including donepezil and a biodegradable polymer, and the microparticles are in a form in which donepezil is uniformly distributed in a spherical biodegradable polymer. The present invention may maintain the effect of preventing or treating the cognitive impairment-related disease for 1 month by a single injection in order to eliminate the inconvenience of having to take the composition daily, and as the present invention is prepared by maintaining the average diameters of the particles at a predetermined micrometer size, a foreign body sensation and pain during administration into a patient as an injection is reduced, thereby enabling administration as an injection to be facilitated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.