Method for post-processing liver MRI images to obtain a reconstructed map of the internal magnetic susceptibility

US11403752B2 · kind B2 · utility

Assignees

• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• UNIVERSITÉ PARIS DIDEROT—PARIS 7 · FR
• CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS (APHP) · FR
• Universite de Versailles Saint-Quentin-en-Yvelines · FR

Inventors

• Benjamin LEPORQ · Villeurbanne, FR
• Simon Lambert · London, GB
• Bernard VAN BEERS · Paris, FR

Key dates

• Filing date: Sep 12, 2017
• Grant date: Aug 2, 2022
• Expiry date: Sep 19, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/30056
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

In the field of obesity related disease, identification of patients with nonalcoholic steatohepatitis (NASH) would be useful to counsel them more intensively on diet and lifestyle changes and propose new pharmacological treatments. As a consequence, the inventors worked on a method for post-processing images of a region of interest of the liver for reconstructing a map of the internal magnetic susceptibility by using a Bayesian regularization approach to inverse the internal magnetic field. Such method can be implemented on computer and provides better results than other known methods for obesity related disease. This method may be applied for predicting that a subject is at risk of suffering from such disease, diagnosing a disease, identifying a therapeutic or a biomarker and screening compounds useful as a medicine.