Ophthalmic compositions and methods for reducing oxidative damage to an eye lens
US11406591B2 · kind B2 · utility
0Cited by
29References
16Claims
0Family size
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Key dates
| Filing date | Feb 8, 2016 |
| Grant date | Aug 9, 2022 |
| Priority date | — |
| Expiry date | Feb 8, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P27/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of reducing oxidative damage to an eye of a subject are provided. Aspects of the method include intravitreal injection an antioxidant composition consisting essentially of a non-reducing sugar or a hydrate thereof. In some embodiments, the non-reducing sugar is trehalose. The methods can further include surgical removal of at least a portion of the subject's vitreous humor during a vitrectomy. Also provided are ophthalmic compositions, kits and pre-loaded injection devices for use in vitrectomy surgery which find use in the subject methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.