Composition comprising EPA and DHA for an enhanced efficacy of anticancer agents

US11406614B2 · kind B2 · utility

Assignee

• Fresenius Kabi Deutschland GmbH · DE

Inventors

• Martin Westphal · Bad Homburg vor der Höhe, DE
• Edmundo Brito De La Fuente · Friedrichsdorf, DE
• Crispulo Gallegos-Montes · Bad Homburg vor der Höhe, DE
• Silke Baasner · Schöneck, DE
• Stefanie HONNDORF · Bad Homburg vor der Höhe, DE
• Lida Quinchia · Bad Homburg vor der Höhe, DE

Key dates

• Filing date: Oct 5, 2017
• Grant date: Aug 9, 2022
• Expiry date: Apr 12, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the enhancement of the efficacy of anticancer agents by a composition comprising an aqueous phase, an oil phase, EPA and DHA for use in the treatment of solid tumors, wherein EPA and DHA are present in an amount of at least 65% based on the total weight of the oil phase wherein the composition comprises EPA and DHA in a weight ratio between 1:2 and 1:4, or wherein the composition comprises EPA and DHA in a weight ratio between 6:1 and 4:1 and wherein the treatment comprises administering the composition and administering at least one anticancer agent.