P aeruginosa PcrV-linked antigen vaccines
US11406696B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Oct 19, 2016 |
| Grant date | Aug 9, 2022 |
| Priority date | — |
| Expiry date | May 21, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a conjugate comprising an antigen (for example a saccharide antigen) covalently linked to a Pseudomonas aeruginosa PcrV carrier protein comprising an amino acid sequence which is at least 80% identical to the sequence of SEQ ID NO:1-4, wherein the antigen is linked (either directly or through a linker) to an amino acid residue of the P. aeruginosa PcrV carrier protein. The invention also discloses Pseudomonas aeruginosa PcrV proteins that contain glycosylation site consensus sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.