Compounds and their use as selective inhibitors of caspase-2
US11407741B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Sep 26, 2018 |
| Grant date | Aug 9, 2022 |
| Priority date | — |
| Expiry date | Sep 26, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a compound of formula (I): wherein P1, P3, P4 and P5 are amino acid residues or amino acid like structures. The invention also relates to a compound of formula (I) for its use as a Caspase-2 inhibitor and for its therapeutical use. It also concerns the use of a compound of formula (I) as activity base probe to selectively detect Caspase-2 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.