Rotavirus vaccines

US11413346B2 · kind B2 · utility

Assignee

• CureVac AG · DE

Inventors

• Susanne RAUCH · Tübingen, DE
• Benjamin PETSCH · Tübingen, DE

Key dates

• Filing date: Nov 9, 2016
• Grant date: Aug 16, 2022
• Expiry date: Nov 9, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2720/12334
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides mRNA sequences comprising at least one coding region, encoding for at least one epitope of a protein, or of a fragment, variant or derivative thereof, of a virus of the genus rotavirus. Particularly preferred is the protein respectively the protein cleavage product VP8* of rotavirus. The mRNA sequence may be used as a vaccine or generally as a pharmaceutical composition for prophylaxis or treatment of rotavirus infections.