Patent · US Active

Phospholipid derivatives and their use as medicaments

US11414443B2 · kind B2 · utility

0Cited by

2References

14Claims

0Family size

Assignees

USTAV MOLEKULARNI GENETIKY AV CR, V.V.I. · CZ
SMART BRAIN S.R.O. · CZ

Inventors

Michal Dvorak · Praha, CZ
Marta Dvorakova · Praha, CZ
Vit Karafiat · Praha, CZ
Jan STURSA · Praha, CZ
Lukas Werner · Hswar, MM
Lucie Janeckova · Praha, CZ

Key dates

Filing date	Mar 29, 2018
Grant date	Aug 16, 2022
Priority date	—
Expiry date	Mar 29, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/704
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to 1-acyl-lysophosphatidyl derivatives of general formula I; in which R is C4 to C30 aliphatic hydrocarbyl chain, R1 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, R2 is selected from H, C10 to C30 acyl or C1 to C10 alkyl, preferably C1 to C6 alkyl, and R3, when present, is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl. These derivatives are intended for the treatment of cancer, in particular melanoma, hepatocarcinoma or GIT carcinomas.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.