System and method for color deconvolution of a slide image to assist in the analysis of tissue specimen
US11417021B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 31, 2020 |
| Grant date | Aug 16, 2022 |
| Priority date | — |
| Expiry date | Jan 31, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30024
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A tissue analysis system and method for the spectral deconvolution of a RGB digital image obtained from a stained biological tissue sample, by estimating the stain component images that are obtained from a staining system configuration, where the reference stain vectors are assumed to be sampled from a known color distribution. The prior knowledge of stain variability of the staining system is adopted as initial reference stain vectors and statistical distribution of their variability. Based on the initial reference stain vectors distribution, the tissue analysis system determines both the reference stain vectors and stain component images of the input image. The image is then deconvoluted based on the reference stain vectors and stain component images.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.