Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases
US11419861B2 · kind B2 · utility
1Cited by
66References
7Claims
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Key dates
| Filing date | Apr 17, 2020 |
| Grant date | Aug 23, 2022 |
| Priority date | — |
| Expiry date | Dec 26, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compositions, therapeutic methods, screening methods, computational methods and biomarkers based upon the elucidation of the interaction among cereblon, its substrates and certain compounds or agents, including small molecules, peptides, and proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.