Functionalized nanoparticles and methods of making and using same
US11419952B2 · kind B2 · utility
3Cited by
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19Claims
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Key dates
| Filing date | May 21, 2018 |
| Grant date | Aug 23, 2022 |
| Priority date | — |
| Expiry date | May 21, 2038 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described is a versatile surface modification approach to, for example, modularly and orthogonally functionalize nanoparticles (NPs) such as, for example, PEGylated nanoparticles, ith various types of different functional ligands (functional groups) on the NP surface. It enables the synthesis of, for example, penta-functional PEGylated nanoparticles integrating a variety of properties into a single NP, e.g., fluorescence detection, specific cell targeting, radioisotope chelating/labeling, ratiometric pH sensing, and drug delivery, while the overall NP size remains, for example, below 10 nm.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.