(S)-n-hydroxy-2-(2-(4-methoxyphenyl)butanamido)thiazole-5-carboxamide and pharmaceutically acceptable salts thereof
US11420947B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jun 10, 2021 |
| Grant date | Aug 23, 2022 |
| Priority date | — |
| Expiry date | Jun 10, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/56
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the compound (S)-n-hydroxy-2-(2-(4-methoxyphenyl) butanamido)thiazole-5-carboxamide, which is a novel histone deacetylase inhibitor. The invention further relates to the use of the compound for the inhibition of histone deacetylating activities of HDAC isoforms and treatment of histone deacetylase (HDAC)-associated diseases. The invention also relates to the pharmaceutical compositions and the making of the pharmaceutical compositions comprising the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.