Rebamipide prodrugs, preparation method and use thereof
US11420963B2 · kind B2 · utility
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2References
12Claims
0Family size
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Key dates
| Filing date | Jun 26, 2013 |
| Grant date | Aug 23, 2022 |
| Priority date | — |
| Expiry date | Jun 26, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are a novel rebamipide prodrug, a method for preparing the same, and use thereof. Also, a pharmaceutical composition comprising the novel rebamipide prodrug as an active ingredient is provided. The rebamipide prodrug is increased 25-fold in absorption rate compared to rebamipide itself, and can be applied to the prophylaxis or therapy of gastric ulcer, acute gastritis, chronic gastritis, xerophthalmia, cancer, osteoarthritis, rheumatoid arthritis, or obesity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.