Patent · US Active

Method for synthesizing amanitins

US11420971B2 · kind B2 · utility

1Cited by

2References

8Claims

0Family size

Assignee

Heidelberg Pharma Research GmbH · DE

Inventors

Werner Simon · Seeheim-Jugenheim, DE
Susanne Werner-Simon · Hüffelsheim, DE
Christian Lutz · Kassel, DE
Christoph Müller · Birkenau, DE
Torsten Hechler · Ladenburg, DE
Michael Kulke · Ladenburg, DE

Key dates

Filing date	Aug 6, 2018
Grant date	Aug 23, 2022
Priority date	—
Expiry date	Mar 16, 2039

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to novel methods for synthesizing amanitin derivatives having an amino group attached to position 6′ of the central tryptophan moiety. The invention furthermore relates to a novel amanitin derivative having an amino group attached to position 6′ of the central tryptophan moiety, novel conjugates of such amanitin derivative, and pharmaceutical compositions comprising such conjugates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.