Anti-infective and anti-inflammatory compounds

US11420995B2 · kind B2 · utility

Assignee

• SYNOVO GMBH · DE

Inventors

• Nikolas Pietrzik · Tübingen, DE
• Michael Burnet · Bingen, DE
• Christiane Baeuerlein · Ofterdingen, DE
• Mary Eggers · Herrenberg, DE
• Jan-Hinrich Guse · Asperg, DE
• Ulrike Hahn · Ditzingen, DE
• Simon Strass · Im Loh, DE

Key dates

• Filing date: Mar 2, 2018
• Grant date: Aug 23, 2022
• Expiry date: Mar 2, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K45/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Lysosomally accumulated substances that release a nitroxy group, or a short chain fatty acid or a product of anaerobic metabolism or a thiol or a sulfide often from an ester or similar labile linkage have anti-inflammatory, anti-cancer and anti-bacterial activity. They are useful in treating infectious, inflammatory and malignant disease.