Antibody/T-cell receptor chimeric constructs and uses thereof
US11421013B2 · kind B2 · utility
2Cited by
43References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 21, 2016 |
| Grant date | Aug 23, 2022 |
| Priority date | — |
| Expiry date | Mar 20, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM capable of recruiting at least one TCR-associated signaling module. Also provided are methods of making and using these constructs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.