System based on a new nitrile hydratase for highly efficient catalytic hydration reaction of aliphatic dinitriles
US11421214B2 · kind B2 · utility
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Key dates
| Filing date | Oct 25, 2019 |
| Grant date | Aug 23, 2022 |
| Priority date | — |
| Expiry date | Aug 9, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y402/01084
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention belongs to the technical field of green chemistry, and provides a novel system based on a new nitrile hydratase for highly efficient catalytic conversion of aliphatic dinitriles. The invention discloses a new application of nitrile hydratase using Rhodococcus erythropolis CCM 2595 in catalyzing aliphatic dinitrile. In particular, the enzyme can regioselectivity catalyze the formation of 5-cyanopyramides from adiponitrile with high reaction rate under mild reaction conditions, which provides a new method for the industrial production of 5-cyanopyramides.
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