Microarray based multiplex pathogen analysis and uses thereof
US11421224B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Oct 11, 2018 |
| Grant date | Aug 23, 2022 |
| Priority date | — |
| Expiry date | Oct 11, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5308
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein is a method for manufacturing a 3-dimensional lattice microarray system for DNA sequence detection and analysis. A solid support is contacted with a formulation containing a plurality of nucleic acid probes, a plurality of bifunctional polymer liners and a solvent mixture of water and a water-miscible liquid. In a first attachment reaction the bifunctional polymer linkers are attached to the solid support and the water is evaporated. In a second attachment reaction the nucleic acid probes are attached to the bifunctional polymer linker.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.