Mutant of hemagglutinin protein of H3N2 subtype influenza virus and use thereof

US11426459B2 · kind B2 · utility

Assignee

• XIAMEN UNIVERSITY · CN

Inventors

• Yixin Chen · Nanhu, CN
• Chenguang Shen · Xiamen, CN
• Junyu Chen · Miaocheng, CN
• Mengya Zhang · Xiamen, CN
• Limin Zhang · Beijing, CN
• Ningshao Xia · Fujian, CN

Key dates

• Filing date: Oct 10, 2018
• Grant date: Aug 30, 2022
• Expiry date: Oct 10, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2760/16171
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure relates to a mutant of hemagglutinin protein of H3N2 subtype influenza virus and use thereof. In addition, the disclosure also relates to a pharmaceutical composition (e.g., a vaccine) comprising the mutant, a method for preparing the mutant, and a method of using the mutant for prevention and/or treatment of an infection of influenza virus and/or a disease (e.g., an influenza) caused by the infection.