Acoustophoretic lysis devices and methods
US11426727B2 · kind B2 · utility
1Cited by
49References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 26, 2021 |
| Grant date | Aug 30, 2022 |
| Priority date | — |
| Expiry date | Apr 26, 2041 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0487
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Lysis devices, methods, and systems are disclosed including a lysis device comprising a sample vessel having an outer surface, a microchannel within the confines of the outer surface, a first port extending through the outer surface to the microchannel, and a second port extending through the outer surface to the microchannel; and an acoustic transducer bonded to the outer surface of the sample vessel to form a monolithic structure, the acoustic transducer configured to emit ultrasonic acoustic waves into and/or to induce shear forces into a blood sample within the microchannel, thereby rupturing the blood cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.