Ligands selective to alpha 6 subunit-containing GABAA receptors and their methods of use
US11427582B2 · kind B2 · utility
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Key dates
| Filing date | Oct 23, 2020 |
| Grant date | Aug 30, 2022 |
| Priority date | — |
| Expiry date | Oct 23, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are novel pyrazoloquinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.