Antibody inhibitors of IL-38 and methods of use thereof for treating or reducing the likelihood of cancer in a subject

US11427630B2 · kind B2 · utility

Assignee

• Fraunhofer-Gesellschaft zur förderung der angewandten Forschung e.V. · DE

Inventors

• Andreas WEIGERT · Hofheim, DE
• Javier MORA · San José, CR
• Bernhard Brüne · Wiehl, DE
• Mateusz PUTYRSKI · Munich, DE
• Michael Parnham · Bad Soden am Taunus, DE
• Andreas Ernst · Worms, DE

Key dates

• Filing date: May 7, 2018
• Grant date: Aug 30, 2022
• Expiry date: Sep 10, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An inhibitor of IL-38 is useful for treating and/or preventing cancer in a subject. A pharmaceutical composition can include an inhibitor of IL-38. A method for treating and/or preventing cancer is carried out by administering an inhibitor of IL-38 in a therapeutically effective amount. Another method is useful for identifying an inhibitor of IL-38.