Polynucleotides encoding humanized antibodies against CEACAM1
US11427647B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Dec 2, 2019 |
| Grant date | Aug 30, 2022 |
| Priority date | — |
| Expiry date | Dec 31, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/70503
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Humanized antibodies, capable of specific binding to human CEACAM1 molecules containing human-to-murine back-mutations in non-CDR variable regions, and their encoding polynucleotide sequences are provided. Pharmaceutical compositions comprising these antibodies as well as methods of their use in treating and diagnosing cancer and other conditions are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.