Methods and uses for remotely triggered protease activity measurements
US11428689B2 · kind B2 · utility
5Cited by
34References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 5, 2017 |
| Grant date | Aug 30, 2022 |
| Priority date | — |
| Expiry date | Jun 2, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure relates to methods and products associated with in vitro and in vivo protease activity measurements and enzyme profiling. Some aspects of the present disclosure relate to measuring remotely triggered protease activity. In particular, the disclosure relates to methods of in vivo processing of exogenous molecules followed by detection of signature molecules as representative of the presence or absence of active enzymes associated with disease or conditions. The disclosure also relates to products, kits, and databases for use in the methods of the disclosure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.