Systems, methods, and media for decoding observed spike counts for spiking cells

US11429847B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Sean Perkins · New York, US
• Mark Churchland · New York, US
• Karen Schroeder · San Diego, US
• John Cunningham · Saratoga Springs, US

Key dates

• Filing date: Jan 31, 2022
• Grant date: Aug 30, 2022
• Expiry date: Jan 31, 2042

Classification

• Technology area (CPC G): Physics
• CPC primary: G16H20/30
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Mechanisms including: receiving a first set of observed spike counts (FSoOSCs) for the spiking cells; determining a set of probabilities (SoPs) by: retrieving the SoPs from stored information (SI); or calculating the SopS based on the SI, wherein the SI regards possible biological states (BSs) of a subject, wherein each of the possible BSs belongs to at least one of a plurality of time sequences (PoTSs) of BSs, wherein each of the PoTSs of BSs corresponds to a possible action of the subject, and wherein each probability in the set of probabilities indicates a likelihood of observing a possible spike count for one of the plurality of spiking cells; identifying using a hardware processor a first identified BS of the subject from the possible BSs based on the FSoOSCs and the set of probabilities; and determining an action to be performed based on the first identified BS.