Biomaterial based on aligned fibers, arranged in a gradient interface, with mechanical reinforcement for tracheal regeneration and repair
US11432922B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 2, 2021 |
| Grant date | Sep 6, 2022 |
| Priority date | — |
| Expiry date | Nov 2, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/22
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An implant can include a plurality of polymeric fibers associated together into a fibrous body. The fibrous body is capable of being shaped to fit a tracheal defect and capable of being secured in place by suture or by bioadhesive. The fibrous body can have aligned fibers (e.g., circumferentially aligned) or unaligned fibers. The fibrous body can be electrospun. The fibrous body can have a first characteristic in a first gradient distribution across at least a portion of the fibrous body. The fibrous body can include one or more structural reinforcing members, such as ribbon structural reinforcing members, which can be embedded in the plurality of fibers. The fibrous body can include one or more structural reinforcing members bonded to the fibers with liquid polymer as an adhesive, the liquid polymer having a substantially similar composition of the fibers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.