Preparation of microparticulate methylprednisolone acetate suspension
US11433084B2 · kind B2 · utility
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14Claims
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Assignee
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Key dates
| Filing date | Feb 14, 2020 |
| Grant date | Sep 6, 2022 |
| Priority date | — |
| Expiry date | Feb 14, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a process for preparation of a water-insoluble steroid composition by moist heat sterilization. The invention particularly relates to a process for preparation of a water-insoluble steroid composition comprising moist heat sterilization or autoclaving of an aqueous slurry of methylprednisolone acetate in the presence of a specified quantity of polysorbate. The suspensions prepared by using the current invention exhibited good physical and chemical stability. Compositions related thereto are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.