Inhibitors of SOX18 protein activity for treating angiogenesis-and/or lymphangiogenesis-related diseases
US11434190B2 · kind B2 · utility
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Key dates
| Filing date | Dec 21, 2017 |
| Grant date | Sep 6, 2022 |
| Priority date | — |
| Expiry date | Jan 2, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C233/65
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compounds of a formula provided herein that show efficacy in the inhibition of SOX18 protein activity, and in particular with respect to the ability of SOX18 to bind DNA and/or particular protein partners. Further, methods of treating angiogenesis- and/or lymphangiogenesis-related diseases, disorders or conditions, such as cancer metastasis and vascular cancers, are provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.