Solid form of dihydropyrimidine compound and preparation method therefor and use thereof

US11434235B2 · kind B2 · utility

Assignee

• SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. · CN

Inventors

• Tianming Wang · Shanghai, CN
• Chengxi Yang · Sichuan, CN
• Jiaqiang Cai · Lanark, GB
• Wei Liu · Hangzhou City, CN
• Baolei Zhang · Shanghai, CN
• Qiang Tian · Sichuan, CN
• Shuai SONG · Chengdu, CN
• Hao Hu · Longbeilingcun, CN
• Weibiao Han · Chengdu, CN
• Youqiang Li · Chengdu, CN
• Xing CHEN · Zhongshan, CN
• Lichun Wang · Sichuan, CN
• Jingyi Wang · Chengdu, CN

Key dates

• Filing date: May 6, 2019
• Grant date: Sep 6, 2022
• Expiry date: Sep 21, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/13
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are a solid form of (E)-3-((R)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)acrylic acid, a preparation method therefor, a pharmaceutical composition comprising same, and the use thereof in the preparation of drugs for preventing or treating viral diseases.