Lipid-polymer based complexation and delivery of nucleic acids
US11434317B2 · kind B2 · utility
1Cited by
3References
17Claims
0Family size
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Key dates
| Filing date | Apr 15, 2020 |
| Grant date | Sep 6, 2022 |
| Priority date | — |
| Expiry date | Jul 22, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F2438/03
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel polymers, crosslinked polymer-nucleic acid complexes, lipid-polymer-nucleic acid-based complexation and nanoassemblies, and nanoassembly-based intracellular delivery of nucleic acids and controlled release thereof upon degradation of the nanoassemblies in response to specific microenvironment in the cell, and compositions and methods of preparation and use thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.