Fractional abundance of polynucleotide sequences in a sample
US11435338B2 · kind B2 · utility
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41Claims
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Key dates
| Filing date | Oct 24, 2017 |
| Grant date | Sep 6, 2022 |
| Priority date | — |
| Expiry date | Oct 24, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44791
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methods and compositions for determining an improved estimate of the true fractional abundance of target analytes (e.g., specific polynucleotide sequences) in a sample using a nanopore sensor, e.g., by correcting errors inherent to identifying and correlating electrical signals to amounts of a target analyte or reference analyte in a sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.