Method of evaluating drug resistance and treatment effect
US11435353B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Dec 4, 2018 |
| Grant date | Sep 6, 2022 |
| Priority date | — |
| Expiry date | Apr 18, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/57488
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method of evaluating drug resistance in hormone therapy including the following steps. Firstly, a primary level of TRBP in a subject is measured, and an effective amount of tamoxifen, an active form of tamoxifen or an analogous of tamoxifen is provided to the subject. Then, a level of TRBP in the subject is measured after providing tamoxifen, the active form of tamoxifen or the analogous of tamoxifen. Finally, a level change of TRBP in the subject is discriminated to determine a tamoxifen resistance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.