Antiproliferative compounds and bispecific antibody against BCMA and CD3 for combined use
US11439637B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | May 22, 2019 |
| Grant date | Sep 13, 2022 |
| Priority date | — |
| Expiry date | Aug 19, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein is are methods of using 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof and a bispecific antibody specifically binding to human B cell maturation antigen (BCMA) and to human CD3ε (CD3) provided herein, in treating, preventing or managing multiple myeloma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.