Ophthalmic compositions

US11439661B2 · kind B2 · utility

Assignee

• ALCON INC. · CH

Inventors

• Steve Yun Zhang · Sugar Hill, US
• Richard Charles Breitkopf · Dunwoody, US
• Daqing Wu · Suwanee, US
• Junhao Ge · Johns Creek, US
• Maria F. Gubitosi Raspino · Lilburn, US
• Augustine Twum Kumi · Grayson, US
• Wei Liang · Johns Creek, US

Key dates

• Filing date: Jun 25, 2020
• Grant date: Sep 13, 2022
• Expiry date: Oct 20, 2040

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is generally related to topical ophthalmic compositions comprising: from about 0.05 w/v % to about 5 w/v % of galactomannan polymer; a cis-diol and about 0.5 w/v % to about 10 w/v % of a hydrophilic copolymer which comprises (a) arylborono-containing repeating units each having a boronic acid, (b) repeating units of at least one phosphorylcholine-containing vinylic monomer, and (c) acrylic monomeric units of at least one acrylic monomer having 3 to 16 carbon atoms, the ophthalmic composition is substantially free of a borate for improving lubrication, hydration and drug delivery property.