Patent · US Active

Process for the preparation of ribociclib and its salts

US11440912B2 · kind B2 · utility

0Cited by

5References

11Claims

0Family size

Assignee

Fresenius Kabi Oncology Ltd. · IN

Inventors

Sarbjot Singh Sokhi · Amritsar, IN
Govind Singh · Ghaziabad, IN
Saswata Lahiri · Sindhar, IN
Maneesh Kumar Pandey · Barwala, IN
Raj Tiwari · Manesar, IN
Sonu Prasad SHUKLA · Sindhar, IN
Sachin Musmade · Sindhar, IN
Heena Dua · Sindhar, IN
Walter Cabri · Sant Celoni, ES

Key dates

Filing date	Oct 26, 2018
Grant date	Sep 13, 2022
Priority date	—
Expiry date	Oct 26, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to a process for the preparation of ribociclib of formula V or its salts. The invention provides novel crystalline forms of ribociclib succinate and ribociclib trifluoroacetate. The present invention also relates to pharmaceutical compositions comprising a crystalline form of ribociclib succinate and at least a pharmaceutically acceptable carrier. It further relates to the use of such compositions in the treatment of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.