Patent · US Active

Polymyxin B component or salt thereof, and preparation and application thereof

US11440940B2 · kind B2 · utility

0Cited by

1References

6Claims

0Family size

Assignee

SPH NO.1 BIOCHEMICAL & PHARMACEUTICAL CO., LTD. · CN

Inventors

Hanzhi Zhang · Shanghai, CN
Hao Liu · Beijing, CN
Zhenhui Huang · Shanghai, CN
Ning Sun · Fremont, US
Wenyan Luo · Shanghai, CN
Jinguo Ding · Shanghai, CN
Xiaofen Liu · Shanghai, CN
Xingchen Bian · Shanghai, CN

Key dates

Filing date	Feb 26, 2021
Grant date	Sep 13, 2022
Priority date	—
Expiry date	Feb 26, 2041

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A polymyxin B component or salts thereof, and a preparation and application thereof. The polymyxin B component includes six α,γ-diaminobutyric acids respectively at positions 1, 3-5 and 8-9, two threonine residues at positions 2 and 10, a phenylalanine residue at position 6 and a leucine residue at position 7 linked in sequence. The threonine residue at position 10 is linked to the α,γ-diaminobutyric acid at position 4 by an amido bond, and the α,γ-diaminobutyric acid at position 1 is linked to 6-methyloctyl-2-enoyl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.