Culture media comprising n-Acyl-X-glutamine dipeptides

US11441119B2 · kind B2 · utility

Assignee

• Evonik Operations GmbH · DE

Inventors

• Guenter Knaup · Bruchköbel, DE
• Friedhelm Merz · Nierstein, DE

Key dates

• Filing date: Mar 2, 2018
• Grant date: Sep 13, 2022
• Expiry date: Jun 6, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2500/90
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed herein is a cell culture media containing L-glutamine from a set of N-acylated dipeptides Acyl-X-Q, and L-glutamine from a set of other glutamine-sources Qsource in a defined molar ratio R=n(Acyl-X-Q)/n(Qsource), wherein the variables X, Q, Acyl, R, n(Acyl-X-Q) and n(Qsource) are defined in the general disclosure. Processes of using the cell culture media are also described herein.