Method and apparatus for identifying a Raman spectrum from background fluorescence
US11441949B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 5, 2021 |
| Grant date | Sep 13, 2022 |
| Priority date | — |
| Expiry date | Apr 5, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06N20/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and system for identifying a Raman spectrum component of an observed spectrum is provided. The observed spectrum is produced by interrogating a material such as a tissue sample with light at the one or more predetermined wavelengths, and the observed spectrum includes a background fluorescence component representative of fluorescent emissions resulting from the light interrogation and a Raman spectrum component representative of a Raman scattering resulting from the light interrogation. The method includes a) creating a reconstructed fluorescence spectrum representative of the background fluorescence component of the observed spectrum using one or more empirically determined fluorescent spectral profiles; and b) identifying the Raman spectrum of the observed spectrum using the reconstructed fluorescence spectrum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.