Patent · US Active

System and method for dynamic multiple contrast enhanced, magnetic resonance fingerprinting (DMCE-MRF)

US11442127B2 · kind B2 · utility

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8Claims
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Key dates

Filing dateApr 6, 2018
Grant dateSep 13, 2022
Priority date
Expiry dateDec 10, 2038

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG06T2207/30016
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure provides a method of DDCE-MRF. The method can include: a) introducing two or more contrast agents to a region of interest (ROI) of a subject, the two or more contrast agents having different relaxivities; b) measuring a T1 relaxation time and a T2 relaxation time for locations within the ROI using magnetic resonance fingerprinting (MRF); c) determining, using equations that relate the different relaxivities, the T1 relaxation time, the T2 relaxation time, and concentrations of the two or more contrast agents, the concentrations of the two or more contrast agents for each of the locations within the ROI; and d) producing an image depicting the ROI based, at least in part, on the concentrations of the two or more contrast agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.